Tianeptine Sodium Formulation

Tianeptine Sodium is a drug primarily designed to be used in the treatment of depression disorders. It has antidepressant and antianxiety properties with a variety of effects on the body such as anxiety suppression, motivational enhancement, cognitive euphoria, rejuvenation and focus enhancement. The drug has also been used for the treatment of asthma and irritable bowel syndrome.

Tianeptine’s primary mode of action involves increasing serotonin uptake in the brain and in platelets. It also regulates the activity of the glutamatergic system, which is majorly responsible for its antidepressant properties. Tianeptine works by modulating actions of glutamate to help keep stress and depression in check.

Tianeptine is manufactured independently and later formulated into either sulfate or sodium salt. It is believed that the salts make the drug achieve maximum absorption, bioavailability, and overall effectiveness. However, the Tianeptine Sodium is the most popular formulation since it was the first to hit the market, and it’s also the most commonly prescribed by doctors. Compared to the sulfate version, Tianeptine Sodium is absorbed faster by the body and its effects can be felt within a few minutes of taking the drug.

When it comes to packing, Tianeptine Sodium is available in both powder and pill formats. But the powder format is quite rare since it’s not easy to use especially for users new to nootropics. Pills typically come in 12.5mg by weight and are more convenient and easy to handle.


Tianeptine has extremely high potency compared to other common nootropics in the market, therefore, its dosage must be keenly observed in order to get the best possible results and avoid potential side effect. Tianeptine, in general, has a recommended dosage range of between 12.5mg and 25mg per day. However, with Tianeptine Sodium, users are advised to stick to 12.5mg per day, and since it’s easily absorbed and utilized by the body; it should be taken in 2-3 dosage splits spread throughout the day for optimum results.

Tianeptine Sodium Benefits

• It reduces and treats depression and anxiety

It relieves sadness, stress and enhances mood.

• It can treat social anxiety, obsessive, compulsive and eating disorders.

• It can aid in treatment of neurodegenerative diseases such as Alzheimer’s, cerebral aging, and multiple sclerosis

• It has been shown to enhance memory and cognitive functions

• It’s effective in treating Attention Deficit Hyperactivity Disorder

• Protects the brain through its neuroprotective properties

• Has been found effective in patients with asthma and irritable bowel syndrome

• Improves focus and attention

Any potential Side Effects?

Being a nootropic, Tianeptine Sodium is generally safe with no toxicity to human beings. There have been very few reports of Tianeptine causing side effects when used within the recommended dosage range of 12.5mg to 25mg per day. Most cases of notable side effects have been reported in users sensitive to Tianeptine, or in cases where significantly high doses are administered.

Common side effects that have been reported include dry mouth, irregular sleep patterns, dizziness, constipation, and nausea. These, however, can be easily reversed by reducing the dosage or temporarily stopping the use of this drug. In cases where the side effects persist or escalate, be sure to contact your doctor immediately for intervention.


Tianeptine Sodium is a great antidepressant and antianxiety nootropic with a wide range of other benefits such as enhanced focus, improved cognitive functions, and enhanced memory. It’s fast acting compared to its sulfate counterpart; and easy to use too. So whether you simply need to keep your anxiety and depression in check, or you want to hasten the treatment of neurodegenerative diseases such as Alzheimer’s and multiple sclerosis; Tianeptine Sodium has got you covered.

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Nicole Sanders

Hi, I'm Nicole, chief editor at Nootropics Revealed. Learn more about me and my mission here.